MUC2 monoclonal antibody, clone MLP/842
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More Files
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon cancer (A, B) with MUC2 monoclonal antibody, clone MLP/842 (Cat # MAB13368).
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant human MUC2.
Immunogen
Recombinant protein corresponding to full length human MUC2.
Host
Mouse
Theoretical MW (kDa)
520
Reactivity
Human
Specificity
This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3.
Form
Liquid
Purification
Protein A/G purification
Isotype
IgG1, kappa
Recommend Usage
Flow Cytometry (0.5-1 ug/106 cells in 0.1 mL)
Immunofluorescence (1-2 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In 10 mM PBS.
Storage Instruction
Store at -20 to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human colon cancer (A, B) with MUC2 monoclonal antibody, clone MLP/842 (Cat # MAB13368).Immunofluorescence
Flow Cytometry
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Gene Info — MUC2
Entrez GeneID
4583Protein Accession#
Q02817Gene Name
MUC2
Gene Alias
MLP, SMUC
Gene Description
mucin 2, oligomeric mucus/gel-forming
Omim ID
158370Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins produced by many epithelial tissues. The protein encoded by this gene is secreted and forms an insoluble mucous barrier that protects the gut lumen. The protein polymerizes into a gel of which 80% is composed of oligosaccharide side chains by weight. The protein features a central domain containing tandem repeats rich in threonine and proline that varies between 50 and 115 copies in different individuals. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq
Other Designations
mucin 2|mucin 2, intestinal/tracheal|mucin-like protein
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Interactome
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Pathway
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Disease
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