Immunohistochemistry (Formalin-fixed paraffin-embedded sections) of human colon cancer with KRT19 monoclonal antibody, clone A53-B/A2.26 (Cat # MAB11278) at 1:100 using peroxidase-conjugate and DAB chromogen.
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. [provided by RefSeq
40-kDa keratin intermediate filament,cytokeratin 19,keratin, type I cytoskeletal 19,keratin, type I, 40-kd