FGG monoclonal antibody, clone 5A6
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant FGG.
Immunogen
Recombinant protein corresponding to human FGG.
Host
Mouse
Theoretical MW (kDa)
52
Reactivity
Human
Form
Liquid
Isotype
IgG2b
Recommend Usage
ELISA (1:10000)
Western Blot (1:500-1:2000)
Immunofluorescence (1:200-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In ascites (0.03% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Recombinant protein)
Western blot analysis using FGG monoclonal antibody, clone 5A6 (Cat # MAB10649) against human FGG (aa 210-437) recombinant protein. (Expected MW is 51.5 kDa)Immunofluorescence
Immunofluorescence analysis of NIH/3T3 cells using FGG monoclonal antibody, clone 5A6 (Cat # MAB10649) (green) . Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.Enzyme-linked Immunoabsorbent Assay
ELISA measurement of FGG monoclonal antibody, clone 5A6 (Cat # MAB10649) . -
Gene Info — FGG
Entrez GeneID
2266Gene Name
FGG
Gene Alias
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Gene Description
fibrinogen gamma chain
Omim ID
134850Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
fibrinogen, gamma chain|fibrinogen, gamma polypeptide
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Interactome
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