FGG polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against recombinant FGG.
Immunogen
Recombinant protein corresponding to human FGG.
Host
Sheep
Reactivity
Human
Form
Liquid
Recommend Usage
ELISA (1:10000)
Immunodiffusion (1:32)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Enzyme-linked Immunoabsorbent Assay
Immunodiffusion
Immunoelectron Microscopy
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Gene Info — FGG
Entrez GeneID
2266Gene Name
FGG
Gene Alias
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Gene Description
fibrinogen gamma chain
Omim ID
134850Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
fibrinogen, gamma chain|fibrinogen, gamma polypeptide
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Interactome
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Pathway
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Disease
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