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DDR2 monoclonal antibody, clone 3B11E4

  • Catalog # : MAB10622
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant DDR2.
  • Immunogen:
  • Recombinant protein corresponding to human DDR2.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    Immunofluorescence (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In ascites (0.03% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis using DDR2 monoclonal antibody, clone 3B11E4 (Cat # MAB10622) against truncated DDR2 recombinant protein.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human skeletal musle tissues using DDR2 monoclonal antibody, clone 3B11E4 (Cat # MAB10622) .
  • Immunofluorescence
  • Immunofluorescence
  • Confocal immunofluorescence analysis of A-549 cells using DDR2 monoclonal antibody, clone 3B11E4 (Cat # MAB10622) (green) . Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4921
  • Gene Name:
  • DDR2
  • Gene Alias:
  • MIG20a,NTRKR3,TKT,TYRO10
  • Gene Description:
  • discoidin domain receptor tyrosine kinase 2
  • Gene Summary:
  • Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000032332,OTTHUMP00000038368,cell migration-inducing protein 20,discoidin domain receptor family, member 2,hydroxyaryl-protein kinase,migration-inducing gene 16 protein,neurotrophic tyrosine kinase receptor related 3,tyrosylprotein kinase
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