DDR2 recombinant monoclonal antibody, clone 9A9
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More Files
- More Functions
Western Blot
Western Blot analysis of Lane 1: A549 whole cell lysate; Lane 2: SY5Y whole cell lysate; Lane3: A375 whole cell lysate; Lane 4: HepG2 whole cell lysate; Lane 5: Mouse Lung tissue lysate.
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human and mouse DDR2.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human DDR2.
Reactivity
Human, Mouse
Form
Liquid
Purification
Affinity chromatography purification
Isotype
IgG
Recommend Usage
ELISA
Flow Cytometry(1:50-1:200)
Western Blot(1:500-1:2000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH7.4 (150 mM NaCl, 0.02% sodium azide and 50% glycerol)
Storage Instruction
Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western Blot analysis of Lane 1: A549 whole cell lysate; Lane 2: SY5Y whole cell lysate; Lane3: A375 whole cell lysate; Lane 4: HepG2 whole cell lysate; Lane 5: Mouse Lung tissue lysate.Enzyme-linked Immunoabsorbent Assay
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Gene Info — DDR2
Entrez GeneID
4921Protein Accession#
Q16832Gene Name
DDR2
Gene Alias
MIG20a, NTRKR3, TKT, TYRO10
Gene Description
discoidin domain receptor tyrosine kinase 2
Omim ID
191311Gene Ontology
HyperlinkGene Summary
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation, and metabolism. In several cases the biochemical mechanism by which RTKs transduce signals across the membrane has been shown to be ligand induced receptor oligomerization and subsequent intracellular phosphorylation. This autophosphorylation leads to phosphorylation of cytosolic targets as well as association with other molecules, which are involved in pleiotropic effects of signal transduction. RTKs have a tripartite structure with extracellular, transmembrane, and cytoplasmic regions. This gene encodes a member of a novel subclass of RTKs and contains a distinct extracellular region encompassing a factor VIII-like domain. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
OTTHUMP00000032332|OTTHUMP00000038368|cell migration-inducing protein 20|discoidin domain receptor family, member 2|hydroxyaryl-protein kinase|migration-inducing gene 16 protein|neurotrophic tyrosine kinase receptor related 3|tyrosylprotein kinase
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Interactome
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Disease
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