HLA-G monoclonal antibody, clone MEM-G/1
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Specification
Product Description
Mouse monoclonal antibody raised against partial recombinant HLA-G.
Immunogen
Recombinant protein corresponding to heavy chain region (denaturated) of human HLA-G.
Host
Mouse
Reactivity
Human
Specificity
This antibody reacts with denaturated HLA-G heavy chain.
Form
Liquid
Isotype
IgG1
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C. Do not freeze.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry staining with HLA - G monoclonal antibody, clone MEM - G/1 (Cat # MAB0916). A : Pulmonary disseases (paraffin - embedded sections). The antibody MEM - G/1 stains infiltrating macrophages in pulmonary diseases. In the top left corner see the detail of macrophage. B : First - trimester placenta (paraffin - embedded sections). -
Gene Info — HLA-G
Entrez GeneID
3135Gene Name
HLA-G
Gene Alias
MHC-G
Gene Description
major histocompatibility complex, class I, G
Gene Ontology
HyperlinkGene Summary
HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail. [provided by RefSeq
Other Designations
HLA class I molecule|HLA-G histocompatibility antigen, class I, G|MHC class I antigen|OTTHUMP00000039485|b2 microglobulin
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Interactome
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Pathway
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Disease
- Abortion
- Anemia
- Arthritis
- Asthma
- Autoimmune Diseases
- Behcet Syndrome
- Birth Weight
- Bronchial Hyperreactivity
- Carcinoma
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