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Last updated: 2016/12/4

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PRF1 (Human) ELISpot Kit

  • Catalog # : KA3933
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  • Specification
  • Product Description:
  • PRF1 (Human) ELISpot Kit is a sandwich enzyme immunoassay for the quantitative measurement of Human PRF1.
  • Reactivity:
  • Human
  • Storage Instruction:
  • Store the kit at 4°C.
  • Suitable Sample:
  • Cell
  • Sample Volume:
  • 100 uL
  • Label:
  • Biotin-conjugated
  • Detection Method:
  • Colorimetric
  • Regulation Status:
  • For research use only (RUO)
  • Applications
  • Quantification
  • Application Image
  • Quantification
  • Gene Information
  • Entrez GeneID:
  • 5551
  • Gene Name:
  • PRF1
  • Gene Alias:
  • FLH2,HPLH2,MGC65093,P1,PFN1,PFP
  • Gene Description:
  • perforin 1 (pore forming protein)
  • Gene Summary:
  • The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000019759,cytolysin,lymphocyte pore forming protein,perforin 1
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