PRF1 (Human) ELISA Kit
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Specification
Product Description
PRF1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of Human PRF1.
Suitable Sample
Biological Fluids, Cell Culture Supernatant, Plasma, Serum
Sample Volume
100 uL
Label
Biotin-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Intra-Assay
4%
Inter-Assay
4.33%
Calibration Range
62.5 pg/ml-2000 pg/ml
Limit of Detection
<40 pg/ml
Reactivity
Human
Regulation Status
For research use only (RUO)
Quality Control Testing
Standard Curve
The standard curve is for the purpose of demonstration only and should not be used to calculate unknowns. A standard curve should be generated each time the assay is performed.
Storage Instruction
Store the kit at 4°C.
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Applications
Quantification
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Gene Info — PRF1
Entrez GeneID
5551Gene Name
PRF1
Gene Alias
FLH2, HPLH2, MGC65093, P1, PFN1, PFP
Gene Description
perforin 1 (pore forming protein)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules, and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
Other Designations
OTTHUMP00000019759|cytolysin|lymphocyte pore forming protein|perforin 1
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