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Last updated: 2016/11/27

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PRICKLE1 monoclonal antibody (M02), clone 8G5

  • Catalog # : H00144165-M02
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant PRICKLE1.
  • Immunogen:
  • PRICKLE1 (NP_694571, 684 a.a. ~ 756 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • DNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATPDYGLQNPGMNRFLGLYG
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgG2b Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00144165-M02
    Western Blot detection against Immunogen (33.77 KDa) .
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Detection limit for recombinant GST tagged PRICKLE1 is 0.03 ng/ml as a capture antibody.
  • PDF DownloadProtocol Download
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • Sandwich ELISA (Recombinant protein)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • PRICKLE1
  • Gene Alias:
  • EPM1B,FLJ31627,FLJ31937,MGC138902,MGC138903,RILP
  • Gene Description:
  • prickle homolog 1 (Drosophila)
  • Gene Summary:
  • This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq
  • Other Designations:
  • REST (RE-1 silencing transcription factor)/NRSF (neuron-restrictive silencer factor)-interacting LIM domain protein,REST/NRSF-interacting LIM domain protein,prickle-like 1
  • Gene Pathway
  • Related Disease
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