PRICKLE1 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (34.14 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PRICKLE1.
Immunogen
PRICKLE1 (NP_694571, 684 a.a. ~ 756 a.a) partial recombinant protein with GST tag.
Sequence
DNALNLVTERKYSPKDRLRLYTPDNYEKFIQNKSAREIQAYIQNADLYGQYAHATPDYGLQNPGMNRFLGLYG
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.14 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PRICKLE1
Entrez GeneID
144165GeneBank Accession#
NM_153026Protein Accession#
NP_694571Gene Name
PRICKLE1
Gene Alias
EPM1B, FLJ31627, FLJ31937, MGC138902, MGC138903, RILP
Gene Description
prickle homolog 1 (Drosophila)
Omim ID
608500Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3. [provided by RefSeq
Other Designations
REST (RE-1 silencing transcription factor)/NRSF (neuron-restrictive silencer factor)-interacting LIM domain protein|REST/NRSF-interacting LIM domain protein|prickle-like 1
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Interactome
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Pathway
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Disease
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