IL31RA rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human IL31RA peptide using ARM Technology.
Immunogen
A synthetic peptide of human IL31RA is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human IL31RA peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — IL31RA
Entrez GeneID
133396GeneBank Accession#
IL31RAGene Name
IL31RA
Gene Alias
CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, MGC125346, PRO21384
Gene Description
interleukin 31 receptor A
Omim ID
609510Gene Ontology
HyperlinkGene Summary
IL31RA is related to gp130 (IL6ST; MIM 600694), the common receptor subunit for IL6 (MIM 147620)-type cytokines. Oncostatin M receptor (OSMR; MIM 601743) and IL31RA form the heterodimeric receptor through which IL31 (MIM 609509) signals. Expression of IL31RA and OSMR mRNA is induced in activated monocytes, and both mRNAs are constitutively expressed in epithelial cells (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM
Other Designations
GP130 like receptor|OTTHUMP00000122547|class I cytokine receptor|gp130-like monocyte receptor|soluble type I cytokine receptor CRL3
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Interactome
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Disease
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