IL31RA monoclonal antibody (M02), clone 3C9
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant IL31RA.
Immunogen
IL31RA (NP_620586, 21 a.a. ~ 120 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LPAKPENISCVYYYRKNLTCTWSPGKETSYTQYTVKRTYAFGEKHDNCTTNSSTSENRASCSFFLPRITIPDNYTIEVEAENGDGVIKSHMTYWRLENIA
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged IL31RA is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — IL31RA
Entrez GeneID
133396GeneBank Accession#
NM_139017Protein Accession#
NP_620586Gene Name
IL31RA
Gene Alias
CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, MGC125346, PRO21384
Gene Description
interleukin 31 receptor A
Omim ID
609510Gene Ontology
HyperlinkGene Summary
IL31RA is related to gp130 (IL6ST; MIM 600694), the common receptor subunit for IL6 (MIM 147620)-type cytokines. Oncostatin M receptor (OSMR; MIM 601743) and IL31RA form the heterodimeric receptor through which IL31 (MIM 609509) signals. Expression of IL31RA and OSMR mRNA is induced in activated monocytes, and both mRNAs are constitutively expressed in epithelial cells (Dillon et al., 2004 [PubMed 15184896]).[supplied by OMIM
Other Designations
GP130 like receptor|OTTHUMP00000122547|class I cytokine receptor|gp130-like monocyte receptor|soluble type I cytokine receptor CRL3
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Interactome
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Disease
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