EGLN2 monoclonal antibody (M01), clone 2G3
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a full-length recombinant EGLN2.
Immunogen
EGLN2 (AAH36051, 1 a.a. ~ 407 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MDSPCQPQPLSQALPQLPGSSSEPLEPEPGRARMGVESYLPCPLLPSYHCPGVPSEASAGSGTPRATATSTTASPLRDGFGGQDGGELRPLQSEGAAALVTKGCQRLAAQGARPEAPKRKWAEDGGDAPSPSKRPWARQENQEAEREGGMSCSCSSGSGEASAGLMEEALPSAPERLALDYIVPCMRYYGICVKDSFLGAALGGRVLAEVEALKRGGRLRDGQLVSQRAIPPRSIRGDQIAWVEGHEPGCRSIGALMAHVDAVIRHCAGRLGSYVINGRTKAMVACYPGNGLGYVRHVDNPHGDGRCITCIYYLNQNWDVKVHGGLLQIFPEGRPVVANIEPLFDRLLIFWSDRRNPHEVKPAYATRYAITVWYFDAKERAAAKDKYQLASGQKGVQVPVSQPPTPT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (88)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (70.51 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged EGLN2 is 0.3 ng/ml as a capture antibody.ELISA
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Gene Info — EGLN2
Entrez GeneID
112398GeneBank Accession#
BC036051Protein Accession#
AAH36051Gene Name
EGLN2
Gene Alias
DKFZp434E026, EIT6, HIFPH1, HPH-3, PHD1
Gene Description
egl nine homolog 2 (C. elegans)
Omim ID
606424Gene Ontology
HyperlinkGene Summary
The hypoxia inducible factor (HIF) is a transcriptional complex which is involved in oxygen homeostasis. At normal oxygen levels, the alpha subunit of HIF is targeted for degration by prolyl hydroxylation. This gene encodes an enzyme responsible for this posttranslational modification. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq
Other Designations
EGL nine (C.elegans) homolog 2|HIF prolyl hydroxylase 1|HIF-prolyl hydroxylase 1|estrogen-induced tag 6|hypoxia-inducible factor prolyl hydroxylase 1|prolyl hydroxylase domain-containing protein 1
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Interactomes
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