CHMP4C purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CHMP4C protein.
Immunogen
CHMP4C (NP_689497.1, 1 a.a. ~ 233 a.a) full-length human protein.
Sequence
MSKLGKFFKGGGSSKSRAAPSPQEALVRLRETEEMLGKKQEYLENRIQREIALAKKHGTQNKRAALQALKRKKRFEKQLTQIDGTLSTIEFQREALENSHTNTEVLRNMGFAAKAMKSVHENMDLNKIDDLMQEITEQQDIAQEISEAFSQRVGFGDDFDEDELMAELEELEQEELNKKMTNIRLPNVPSSSLPAQPNRKPGMSSTARRSRAASSQRAEEEDDDIKQLAAWAT
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (85)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CHMP4C expression in transfected 293T cell line (H00092421-T02) by CHMP4C MaxPab polyclonal antibody.
Lane 1: CHMP4C transfected lysate(25.63 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CHMP4C
Entrez GeneID
92421GeneBank Accession#
NM_152284Protein Accession#
NP_689497.1Gene Name
CHMP4C
Gene Alias
MGC22825, SNF7-3, Shax3
Gene Description
chromatin modifying protein 4C
Omim ID
610899Gene Ontology
HyperlinkGene Summary
CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM
Other Designations
Snf7 homologue associated with Alix 3
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Interactome
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Pathway
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