MXD3 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MXD3 protein.
Immunogen
MXD3 (NP_112590.1, 1 a.a. ~ 206 a.a) full-length human protein.
Sequence
MEPLASNIQVLLQAAEFLERREREAEHGYASLCPHRSPGPIHRRKKRPPQAPGAQDSGRSVHNELEKRRRAQLKRCLERLKQQMPLGADCARYTTLSLLRRARMHIQKLEDQEQRARQLKERLRSKQQSLQRQLEQLRGLAGAAERERLRADSLDSSGLSSERSDSDQEELEVDVESLVFGGEAELLRGFVAGQEHSYSHGGGAWL
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (81)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MXD3 expression in transfected 293T cell line (H00083463-T01) by MXD3 MaxPab polyclonal antibody.
Lane 1: MXD3 transfected lysate(22.66 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to MXD3 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — MXD3
Entrez GeneID
83463GeneBank Accession#
NM_031300.2Protein Accession#
NP_112590.1Gene Name
MXD3
Gene Alias
BHLHC13, FLJ35523, MAD3, MGC2383, MYX
Gene Description
MAX dimerization protein 3
Omim ID
609450Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq
Other Designations
Max-associated protein 3|Max-interacting transcriptional repressor MAD3
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