MXD3 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-MXD3 full-length
Host
Human
Theoretical MW (kDa)
22.77
Interspecies Antigen Sequence
Mouse (83); Rat (81)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-MXD3 antibody (H00083463-B01) by Western Blots.
SDS-PAGE Gel
MXD3 transfected lysate.
Western Blot
Lane 1: MXD3 transfected lysate ( 22.77 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — MXD3
Entrez GeneID
83463GeneBank Accession#
NM_031300.2Protein Accession#
-Gene Name
MXD3
Gene Alias
BHLHC13, FLJ35523, MAD3, MGC2383, MYX
Gene Description
MAX dimerization protein 3
Omim ID
609450Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq
Other Designations
Max-associated protein 3|Max-interacting transcriptional repressor MAD3
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