GRHL2 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of GRHL2 expression in transfected 293T cell line (H00079977-T01) by GRHL2 MaxPab polyclonal antibody.
Lane 1: GRHL2 transfected lysate(68.75 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to GRHL2 on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human GRHL2 protein.
Immunogen
GRHL2 (NP_079191.1, 1 a.a. ~ 625 a.a) full-length human protein.
Sequence
MSQESDNNKRLVALVPMPSDPPFNTRRAYTSEDEAWKSYLENPLTAATKAMMSINGDEDSAAALGLLYDYYKVPRDKRLLSVSKASDSQEDQEKRNCLGTSEAQSNLSGGENRVQVLKTVPVNLSLNQDHLENSKREQYSISFPESSAIIPVSGITVVKAEDFTPVFMAPPVHYPRGDGEEQRVVIFEQTQYDVPSLATHSAYLKDDQRSTPDSTYSESFKDAATEKFRSASVGAEEYMYDQTSSGTFQYTLEATKSLRQKQGEGPMTYLNKGQFYAITLSETGDNKCFRHPISKVRSVVMVVFSEDKNRDEQLKYWKYWHSRQHTAKQRVLDIADYKESFNTIGNIEEIAYNAVSFTWDVNEEAKIFITVNCLSTDFSSQKGVKGLPLMIQIDTYSYNNRSNKPIHRAYCQIKVFCDKGAERKIRDEERKQNRKKGKGQASQTQCNSSSDGKLAAIPLQKKSDITYFKTMPDLHSQPVLFIPDVHFANLQRTGQVYYNTDDEREGGSVLVKRMFRPMEEEFGPVPSKQMKEEGTKRVLLYVRKETDDVFDALMLKSPTVKGLMEAISEKYGLPVEKIAKLYKKSKKGILVNMDDNIIEHYSNEDTFILNMESMVEGFKVTLMEI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (94); Rat (94)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GRHL2 expression in transfected 293T cell line (H00079977-T01) by GRHL2 MaxPab polyclonal antibody.
Lane 1: GRHL2 transfected lysate(68.75 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to GRHL2 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — GRHL2
Entrez GeneID
79977GeneBank Accession#
NM_024915.1Protein Accession#
NP_079191.1Gene Name
GRHL2
Gene Alias
BOM, DFNA28, FLJ11172, FLJ13782, MGC149294, MGC149295, TFCP2L3
Gene Description
grainyhead-like 2 (Drosophila)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28)
Other Designations
transcription factor CP2-like 3
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Disease
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Publication Reference
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p63 Gene is Regulated by Grainyhead-Like 2 (GRHL2) Through Reciprocal Feedback and Determines Epithelial Phenotype in Human Keratinocytes.
Mehrazarin S, Chen W, Oh JE, Liu ZX, Kang KL, Yi JK, Kim RH, Shin KH, Park NH, Kang MK.
The Journal of Biological Chemistry 2015 Aug; 290(32):19999.
Application：IF, WB-Ce, WB-Tr, Human, NHEK, HaCaT, NHOF, SCC cells.
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A whole-genome RNAi screen identifies an 8q22 gene cluster that inhibits death receptor-mediated apoptosis.
Dompe N, Rivers CS, Li L, Cordes S, Schwickart M, Punnoose EA, Amler L, Seshagiri S, Tang J, Modrusan Z, Davis DP.
PNAS 2011 Oct; 108(43):E943.
Application：WB-Ce, Human, Human breast cancer cell lines.
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p63 Gene is Regulated by Grainyhead-Like 2 (GRHL2) Through Reciprocal Feedback and Determines Epithelial Phenotype in Human Keratinocytes.
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