GRHL2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human GRHL2.
Immunogen
Recombinant protein corresponding to human GRHL2.
Sequence
NRVQVLKTVPVNLSLNQDHLENSKREQYSISFPESSAIIPVSGITVVKAEDFTPVFMAPPVHYPRGDGEEQRVVIFEQTQYDVPSLATHSAYLKDDQRSTPDSTYSESFKDAATEKFRSASVGAEEYMYDQTSSGTFQYTLEATKSLRQK
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human placenta with GRHL2 polyclonal antibody (Cat # PAB30713) shows strong nuclear positivity in trophoblastic cells.Immunofluorescence
Immunofluorescent staining of RT-4 cells with GRHL2 polyclonal antibody (Cat # PAB30713) (Green) shows positivity in plasma membrane and nucleus but excluded from the nucleoli. -
Gene Info — GRHL2
Entrez GeneID
79977Protein Accession#
Q6ISB3Gene Name
GRHL2
Gene Alias
BOM, DFNA28, FLJ11172, FLJ13782, MGC149294, MGC149295, TFCP2L3
Gene Description
grainyhead-like 2 (Drosophila)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcription factor that can act as a homodimer or as a heterodimer with either GRHL1 or GRHL3. Defects in this gene are a cause of non-syndromic sensorineural deafness autosomal dominant type 28 (DFNA28)
Other Designations
transcription factor CP2-like 3
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Disease
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