KREMEN2 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (37.11 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant KREMEN2.
Immunogen
KREMEN2 (NP_078783, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag.
Sequence
MPGYLGCFVDSGAPPALSGPSGTSTKLTVQVCLRFCRMKGYQLAGVEAGYACFCGSESDLARGRLAPATDCDQICFGHPGQLCGGDGRLGVYEVSVGSCQ
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (77); Rat (89)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — KREMEN2
Entrez GeneID
79412GeneBank Accession#
NM_024507Protein Accession#
NP_078783Gene Name
KREMEN2
Gene Alias
KRM2, MGC10791, MGC16709
Gene Description
kringle containing transmembrane protein 2
Omim ID
609899Gene Ontology
HyperlinkGene Summary
This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor that functionally cooperates with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
Other Designations
kringle-containing transmembrane protein 2
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Interactome
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