ACD monoclonal antibody (M01A), clone 1C11-1A7
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of ACD expression in transfected 293T cell line by ACD monoclonal antibody (M01A), clone 1C11-1A7.
Lane 1: ACD transfected lysate (Predicted MW: 57.7 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (85.58 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant ACD.
Immunogen
ACD (AAH16904, 1 a.a. ~ 544 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MPGRCQSDAAMRVNGPASRAPAGWTSGSLHTGPRAGRPRAQARGVRGRGLLLRPRPAKELPLPRKGGAWAPAGNPGPLHPLGVAVGMAGSGRLVLRPWIRELILGSETPSSPRAGQLLEVLQDAEAAVAGPSHAPDTSDVGATLLVSDGTHSVRCLVTREALDTSDWEEKEFGFRGTEGRLLLLQDCGVHVQVAEGGAPAEFYLQVDRFSLLPTEQPRLRVPGCNQDLDVQKKLYDCLEEHLSESTSSNAGLSLSQLLDEMREDQEHQGALVCLAESCLTLEGPCTAPPVTHWAASRCKATGEAVYTVPSSMLCISENDQLILSSLGPCQRTQGPELPPPDPALQDLSLTLIASPPSSPSSSGTPALPGHMSSEESGTSISLLPALSLAAPDPGQRSSSQPSPAICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQALVTRPQKPSLEFKEFVGLPCKNRPPFPRTGATRGAQEPCSVWEPPKRHRDGSAFQYEYEPPCTSLCARVQAARLPPQLMAWALHFLMDAQPGSEPTPM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (59); Rat (61)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (85.58 KDa) .
Storage Buffer
In ascites fluid
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ACD expression in transfected 293T cell line by ACD monoclonal antibody (M01A), clone 1C11-1A7.
Lane 1: ACD transfected lysate (Predicted MW: 57.7 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — ACD
Entrez GeneID
65057GeneBank Accession#
BC016904Protein Accession#
AAH16904Gene Name
ACD
Gene Alias
PIP1, PTOP, TINT1, TPP1
Gene Description
adrenocortical dysplasia homolog (mouse)
Omim ID
609377Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq
Other Designations
POT1 and TIN2 organizing protein|TIN2 interacting protein 1|adrenocortical dysplasia homolog
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Interactome
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Disease
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