ACD MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of ACD expression in transfected 293T cell line (H00065057-T02) by ACD MaxPab polyclonal antibody.
Lane 1: ACD transfected lysate(57.70 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of ACD transfected lysate using anti-ACD MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ACD purified MaxPab mouse polyclonal antibody (B01P) (H00065057-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human ACD protein.
Immunogen
ACD (AAH16904.1, 1 a.a. ~ 544 a.a) full-length human protein.
Sequence
MPGRCQSDAAMRVNGPASRAPAGWTSGSLHTGPRAGRPRAQARGVRGRGLLLRPRPAKELPLPRKGGAWAPAGNPGPLHPLGVAVGMAGSGRLVLRPWIRELILGSETPSSPRAGQLLEVLQDAEAAVAGPSHAPDTSDVGATLLVSDGTHSVRCLVTREALDTSDWEEKEFGFRGTEGRLLLLQDCGVHVQVAEGGAPAEFYLQVDRFSLLPTEQPRLRVPGCNQDLDVQKKLYDCLEEHLSESTSSNAGLSLSQLLDEMREDQEHQGALVCLAESCLTLEGPCTAPPVTHWAASRCKATGEAVYTVPSSMLCISENDQLILSSLGPCQRTQGPELPPPDPALQDLSLTLIASPPSSPSSSGTPALPGHMSSEESGTSISLLPALSLAAPDPGQRSSSQPSPAICSAPATLTPRSPHASRTPSSPLQSCTPSLSPRSHVPSPHQALVTRPQKPSLEFKEFVGLPCKNRPPFPRTGATRGAQEPCSVWEPPKRHRDGSAFQYEYEPPCTSLCARVQAARLPPQLMAWALHFLMDAQPGSEPTPM
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (59); Rat (61)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of ACD expression in transfected 293T cell line (H00065057-T02) by ACD MaxPab polyclonal antibody.
Lane 1: ACD transfected lysate(57.70 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of ACD transfected lysate using anti-ACD MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with ACD purified MaxPab mouse polyclonal antibody (B01P) (H00065057-B01P). -
Gene Info — ACD
Entrez GeneID
65057GeneBank Accession#
BC016904.1Protein Accession#
AAH16904.1Gene Name
ACD
Gene Alias
PIP1, PTOP, TINT1, TPP1
Gene Description
adrenocortical dysplasia homolog (mouse)
Omim ID
609377Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that is involved in telomere function. This protein is one of six core proteins in the telosome/shelterin telomeric complex, which functions to maintain telomere length and to protect telomere ends. Through its interaction with other components, this protein plays a key role in the assembly and stabilization of this complex, and it mediates the access of telomerase to the telomere. Multiple transcript variants encoding different isoforms have been found for this gene. This gene, which is also referred to as TPP1, is distinct from the unrelated TPP1 gene on chromosome 11, which encodes tripeptidyl-peptidase I. [provided by RefSeq
Other Designations
POT1 and TIN2 organizing protein|TIN2 interacting protein 1|adrenocortical dysplasia homolog
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Interactome
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Disease
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