MRPL11 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human MRPL11 protein.
Immunogen
MRPL11 (NP_057134.1, 1 a.a. ~ 192 a.a) full-length human protein.
Sequence
MSKLGRAARGLRKPEVGGVIRAIVRAGLAMPGPPLGPVLGQRGVSINQFCKEFNERTKDIKEGIPLPTKILVKPDRTFEIKIGQPTVSYFLKAAAGIEKGARQTGKEVAGLVTLKHVYEIARIKAQDEAFALQDVPLSSVVRSIIGSARSLGIRVVKDLSSEELAAFQKERAIFLAAQKEADLAAQEEAAKK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (87)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MRPL11 MaxPab polyclonal antibody. Western Blot analysis of MRPL11 expression in A-431.Western Blot (Transfected lysate)
Western Blot analysis of MRPL11 expression in transfected 293T cell line (H00065003-T01) by MRPL11 MaxPab polyclonal antibody.
Lane 1: MRPL11 transfected lysate(21.12 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — MRPL11
Entrez GeneID
65003GeneBank Accession#
NM_016050.2Protein Accession#
NP_057134.1Gene Name
MRPL11
Gene Alias
CGI-113, L11MT, MGC111024, MRP-L11
Gene Description
mitochondrial ribosomal protein L11
Gene Ontology
HyperlinkGene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 5q and 12q. [provided by RefSeq
Other Designations
39S ribosomal protein L11, mitochondrial
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