C12orf5 MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of C12orf5 expression in transfected 293T cell line (H00057103-T01) by C12orf5 MaxPab polyclonal antibody.
Lane 1: C12orf5 transfected lysate(29.7 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human C12orf5 protein.
Immunogen
C12orf5 (NP_065108.1, 1 a.a. ~ 270 a.a) full-length human protein.
Sequence
MARFALTVVRHGETRFNKEKIIQGQGVDEPLSETGFKQAAAAGIFLNNVKFTHAFSSDLMRTKQTMHGILERSKFCKDMTVKYDSRLRERKYGVVEGKALSELRAMAKAAREECPVFTPPGGETLDQVKMRGIDFFEFLCQLILKEADQKEQFSQGSPSNCLETSLAEIFPLGKNHSSKVNSDSGIPGLAASVLVVSHGAYMRSLFDYFLTDLKCSLPATLSRSELMSVTPNTGMSLFIINFEEGREVKPTVQCICMNLQDHLNGLTETR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (72)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of C12orf5 expression in transfected 293T cell line (H00057103-T01) by C12orf5 MaxPab polyclonal antibody.
Lane 1: C12orf5 transfected lysate(29.7 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — C12orf5
Entrez GeneID
57103GeneBank Accession#
NM_020375.2Protein Accession#
NP_065108.1Gene Name
C12orf5
Gene Alias
TIGAR
Gene Description
chromosome 12 open reading frame 5
Omim ID
610775Gene Ontology
HyperlinkGene Summary
This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq
Other Designations
TP53-induced glycolysis and apoptosis regulator|transactivated by NS3TP2 protein
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