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Last updated: 2017/8/13

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C12orf5 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00057103-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-C12orf5 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 29.81
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-C12orf5 antibody (H00057103-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00057103-T01
    C12orf5 transfected lysate.
    Western Blot
    QC Testing of H00057103-T01
    Lane 1: C12orf5 transfected lysate ( 29.81 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • C12orf5
  • Gene Alias:
  • TIGAR
  • Gene Description:
  • chromosome 12 open reading frame 5
  • Gene Summary:
  • This gene is regulated as part of the p53 tumor suppressor pathway and encodes a protein with sequence similarity to the bisphosphate domain of the glycolytic enzyme that degrades fructose-2,6-bisphosphate. The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt. Expression of this protein also protects cells from DNA damaging reactive oxygen species and provides some protection from DNA damage-induced apoptosis. The 12p13.32 region that includes this gene is paralogous to the 11q13.3 region. [provided by RefSeq
  • Other Designations:
  • TP53-induced glycolysis and apoptosis regulator,transactivated by NS3TP2 protein
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