CYP26B1 polyclonal antibody (A01)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CYP26B1.
Immunogen
CYP26B1 (NP_063938, 131 a.a. ~ 230 a.a) partial recombinant protein with GST tag.
Sequence
SNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CYP26B1 polyclonal antibody (A01), Lot # ORU0060223QCS1 Western Blot analysis of CYP26B1 expression in K-562 ( Cat # L009V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — CYP26B1
Entrez GeneID
56603GeneBank Accession#
NM_019885Protein Accession#
NP_063938Gene Name
CYP26B1
Gene Alias
CYP26A2, DKFZp686G0638, MGC129613, P450RAI-2
Gene Description
cytochrome P450, family 26, subfamily B, polypeptide 1
Omim ID
605207Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid. [provided by RefSeq
Other Designations
cytochrome P450 retinoid metabolizing protein|cytochrome P450, family 26, subfamily b, polypeptide 1|retinoic acid-metabolizing cytochrome
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Interactome
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Pathway
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Disease
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Publication Reference
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Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases.
Topletz AR, Thatcher JE, Zelter A, Lutz JD, Tay S, Nelson WL, Isoherranen N.
Biochemical Pharmacology 2012 Jan; 83(1):149.
Application:WB-Ti, Human, Human tissues.
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Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases.
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