CYP26B1 monoclonal antibody (M02), clone 2G7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant CYP26B1.
Immunogen
CYP26B1 (NP_063938, 131 a.a. ~ 230 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SNSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSHPEAINVYQEAQKLTFRMAIRVLLGFSIPEEDLGHLFEVYQQFVDNVFSLPVDLPF
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (95)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CYP26B1 expression in transfected 293T cell line by CYP26B1 monoclonal antibody (M02), clone 2G7.
Lane 1: CYP26B1 transfected lysate (Predicted MW: 57.5 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CYP26B1 is 0.1 ng/ml as a capture antibody.ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to CYP26B1 on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — CYP26B1
Entrez GeneID
56603GeneBank Accession#
NM_019885Protein Accession#
NP_063938Gene Name
CYP26B1
Gene Alias
CYP26A2, DKFZp686G0638, MGC129613, P450RAI-2
Gene Description
cytochrome P450, family 26, subfamily B, polypeptide 1
Omim ID
605207Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene is involved in the specific inactivation of all-trans-retinoic acid to hydroxylated forms, such as 4-oxo-, 4-OH-, and 18-OH-all-trans-retinoic acid. [provided by RefSeq
Other Designations
cytochrome P450 retinoid metabolizing protein|cytochrome P450, family 26, subfamily b, polypeptide 1|retinoic acid-metabolizing cytochrome
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Interactome
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Pathway
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Disease
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