Nucleocytoplasmic transport of the RNA-binding protein CELF2 regulates neural stem cell fates. Melissa J MacPherson, Sarah L Erickson, Drayden Kopp, Pengqiang Wen, Mohamad-Reza Aghanoori, Shreeya Kedia, Kaylan M L Burns, Antonio Vitobello, Frederic Tran Mau-Them, Quentin Thomas, Nina B Gold, William Brucker, Louise Amlie-Wolf, Karen W Gripp, Olaf Bodamer, Laurence Faivre, Mikko Muona, Lara Menzies, Julia Baptista, Katie Guegan, Alison Male, Xing-Chang Wei, Guiqiong He, Quan Long, A Micheil Innes, Guang Yang.Cell Rep. 2021 Jun 8;35(10):109226. doi: 10.1016/j.celrep.2021.109226.
Applications
Western Blot (Cell lysate)
EIF4ENIF1 MaxPab polyclonal antibody. Western Blot analysis of EIF4ENIF1 expression in Hela S3 NE.
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq