STRADB polyclonal antibody (A01)
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More Files
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Western Blot (Cell lysate)
STRADB polyclonal antibody (A01), Lot # 061025JCS1 Western Blot analysis of STRADB expression in HeLa ( Cat # L013V1 ).
Western Blot detection against Immunogen (36.56 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant STRADB.
Immunogen
STRADB (NP_061041, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag.
Sequence
MSLLDCFCTSRTQVESLRPEKQSETSIHQYLVDEPTLSWSRPSTRASEVLCSTNVSHYELQVEIGRGFDNLTSVHLARHTPTGTLVTIKITNLEN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.56 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
STRADB polyclonal antibody (A01), Lot # 061025JCS1 Western Blot analysis of STRADB expression in HeLa ( Cat # L013V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — STRADB
Entrez GeneID
55437GeneBank Accession#
NM_018571Protein Accession#
NP_061041Gene Name
STRADB
Gene Alias
ALS2CR2, CALS-21, ILPIP, ILPIPA, MGC102916, PAPK, PRO1038
Gene Description
STE20-related kinase adaptor beta
Omim ID
607333Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered, and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11, a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm, and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein, and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes, located on chromosomes 1 and 7, have been found for this gene. [provided by RefSeq
Other Designations
ILP-interacting protein ILPIPA|STRAD beta|amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 2|pseudokinase ALS2CR2
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Interactome
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