XAF1 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of XAF1 expression in transfected 293T cell line (H00054739-T01) by XAF1 MaxPab polyclonal antibody.
Lane1:BIRC4BP transfected lysate(33.11 KDa).
Lane2:Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to BIRC4BP on HeLa cell. [antibody concentration 10 ug/ml]
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human XAF1 protein.
Immunogen
XAF1 (NP_059993.2, 1 a.a. ~ 301 a.a) full-length human protein.
Sequence
MEGDFSVCRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQVGCTMCQQSMQKSSLEFHKANECQERPVECKFCKLDMQLSKLELHESYCGSRTELCQGCGQFIMHRMLAQHRDVCRSEQAQLGKGERISAPEREIYCHYCNQMIPENKYFHHMGKCCPDSEFKKHFPVGNPEILPSSLPSQAAENQTSTMEKDVRPKTRSINRFPLHSESSSKKAPRSKNKTLDPLLMSEPKPRTSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNFS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (45); Rat (49)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of XAF1 expression in transfected 293T cell line (H00054739-T01) by XAF1 MaxPab polyclonal antibody.
Lane1:BIRC4BP transfected lysate(33.11 KDa).
Lane2:Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to BIRC4BP on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — XAF1
Entrez GeneID
54739GeneBank Accession#
NM_017523.2Protein Accession#
NP_059993.2Gene Name
XAF1
Gene Alias
BIRC4BP, HSXIAPAF1, XIAPAF1
Gene Description
XIAP associated factor 1
Omim ID
606717Gene Ontology
HyperlinkGene Summary
X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM
Other Designations
BIRC4 binding protein
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Interactome
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