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Last updated: 2017/1/15
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XAF1 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00054739-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human XAF1 protein.
  • Immunogen:
  • XAF1 (NP_059993.2, 1 a.a. ~ 301 a.a) full-length human protein.
  • Sequence:
  • MEGDFSVCRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQVGCTMCQQSMQKSSLEFHKANECQERPVECKFCKLDMQLSKLELHESYCGSRTELCQGCGQFIMHRMLAQHRDVCRSEQAQLGKGERISAPEREIYCHYCNQMIPENKYFHHMGKCCPDSEFKKHFPVGNPEILPSSLPSQAAENQTSTMEKDVRPKTRSINRFPLHSESSSKKAPRSKNKTLDPLLMSEPKPRTSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNFS
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of XAF1 expression in transfected 293T cell line (H00054739-T01) by XAF1 MaxPab polyclonal antibody.

    Lane1:BIRC4BP transfected lysate(33.11 KDa).
    Lane2:Non-transfected lysate.
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  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • XAF1
  • Gene Alias:
  • BIRC4BP,HSXIAPAF1,XIAPAF1
  • Gene Description:
  • XIAP associated factor 1
  • Gene Summary:
  • X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM
  • Other Designations:
  • BIRC4 binding protein
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