BIRC4BP 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
- More Functions
SDS-PAGE Gel
XAF1 transfected lysate.
Western Blot
Lane 1: XAF1 transfected lysate ( 33.22 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BIRC4BP full-length
Host
Human
Theoretical MW (kDa)
33.22
Interspecies Antigen Sequence
Mouse (45); Rat (49)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BIRC4BP antibody (H00054739-B01) by Western Blots.
SDS-PAGE Gel
XAF1 transfected lysate.
Western Blot
Lane 1: XAF1 transfected lysate ( 33.22 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — XAF1
Entrez GeneID
54739GeneBank Accession#
NM_017523.2Protein Accession#
NP_059993.2Gene Name
XAF1
Gene Alias
BIRC4BP, HSXIAPAF1, XIAPAF1
Gene Description
XIAP associated factor 1
Omim ID
606717Gene Ontology
HyperlinkGene Summary
X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM
Other Designations
BIRC4 binding protein
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