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BIRC4BP 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00054739-T01
  • Visit Frequency :
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-BIRC4BP full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 33.22
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-BIRC4BP antibody (H00054739-B01) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00054739-T01
    XAF1 transfected lysate.
    Western Blot
    QC Testing of H00054739-T01
    Lane 1: XAF1 transfected lysate ( 33.22 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Gene Name:
  • XAF1
  • Gene Alias:
  • BIRC4BP,HSXIAPAF1,XIAPAF1
  • Gene Description:
  • XIAP associated factor 1
  • Gene Summary:
  • X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM
  • Other Designations:
  • BIRC4 binding protein
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