WNT4 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Western Blot (Tissue lysate)
WNT4 MaxPab polyclonal antibody. Western Blot analysis of WNT4 expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of WNT4 expression in transfected 293T cell line (H00054361-T01) by WNT4 MaxPab polyclonal antibody.
Lane 1: WNT4 transfected lysate(38.61 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human WNT4 protein.
Immunogen
WNT4 (NP_110388.2, 1 a.a. ~ 351 a.a) full-length human protein.
Sequence
MSPRSCLRSLRLLVFAVFSAAASNWLYLAKLSSVGSISEEETCEKLKGLIQRQVQMCKRNLEVMDSVRRGAQLAIEECQYQFRNRRWNCSTLDSLPVFGKVVTQGTREAAFVYAISSAGVAFAVTRACSSGELEKCGCDRTVHGVSPQGFQWSGCSDNIAYGVAFSQSFVDVRERSKGASSSRALMNLHNNEAGRKAILTHMRVECKCHGVSGSCEVKTCWRAVPPFRQVGHALKEKFDGATEVEPRRVGSSRALVPRNAQFKPHTDEDLVYLEPSPDFCEQDMRSGVLGTRGRTCNKTSKAIDGCELLCCGRGFHTAQVELAERCSCKFHWCCFVKCRQCQRLVELHTCR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
WNT4 MaxPab polyclonal antibody. Western Blot analysis of WNT4 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of WNT4 expression in transfected 293T cell line (H00054361-T01) by WNT4 MaxPab polyclonal antibody.
Lane 1: WNT4 transfected lysate(38.61 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — WNT4
Entrez GeneID
54361GeneBank Accession#
NM_030761Protein Accession#
NP_110388.2Gene Name
WNT4
Gene Alias
SERKAL, WNT-4
Gene Description
wingless-type MMTV integration site family, member 4
Gene Ontology
HyperlinkGene Summary
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family, and is the first signaling molecule shown to influence the sex-determination cascade. It encodes a protein which shows 98% amino acid identity to the Wnt4 protein of mouse and rat. This gene and a nuclear receptor known to antagonize the testis-determining factor play a concerted role in both the control of female development and the prevention of testes formation. This gene and another two family members, WNT2 and WNT7B, may be associated with abnormal proliferation in breast tissue. Mutations in this gene can result in Rokitansky-Kuster-Hauser syndrome and in SERKAL syndrome. [provided by RefSeq
Other Designations
OTTHUMP00000002937|OTTHUMP00000044725|WNT-4 protein
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Interactome
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Pathway
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Disease
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