DUOX1 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (35.79 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant DUOX1.
Immunogen
DUOX1 (NP_059130, 941 a.a. ~ 1028 a.a) partial recombinant protein with GST tag.
Sequence
VEVPEVIKDLCRRASYISQDMICPSPRVSARCSRSDIETELTPQRLQCPMDTDPPQEIRRRFGKKVTSFQPLLFTEAHREKFQRSCLH
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (81)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.79 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — DUOX1
Entrez GeneID
53905GeneBank Accession#
NM_017434Protein Accession#
NP_059130Gene Name
DUOX1
Gene Alias
LNOX1, MGC138840, MGC138841, NOXEF1, THOX1
Gene Description
dual oxidase 1
Omim ID
606758Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX2. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq
Other Designations
NADPH thyroid oxidase 1|flavoprotein NADPH oxidase|nicotinamide adenine dinucleotide phosphate oxidase
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Interactome
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Disease
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