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Last updated: 2016/12/4
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DPH5 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00051611-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human DPH5 protein.
  • Immunogen:
  • DPH5 (NP_001070862.1, 1 a.a. ~ 285 a.a) full-length human protein.
  • Sequence:
  • MLYLIGLGLGDAKDITVKGLEVVRRCSRVYLEAYTSVLTVGKEALEEFYGRKLVVADREEVEQEADNILKDADISDVAFLVVGDPFGATTHSDLVLRATKLGIPYRVIHNASIMNAVGCCGLQLYKFGETVSIVFWTDTWRPESFFDKVKKNRQNGMHTLCLLDIKVKEQSLENLIKGRKIYEPPRYMSVNQAAQQLLEIVQNQRIRGEEPAVTEETLCVGLARVGADDQKIAAGTLRQMCTVDLGEPLHSLIITGGSIHPMEMEMLSLFSIPENSSESQSINGL
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of DPH5 expression in transfected 293T cell line (H00051611-T01) by DPH5 MaxPab polyclonal antibody.

    Lane 1: DPH5 transfected lysate(31.35 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Gene Name:
  • DPH5
  • Gene Alias:
  • AD-018,CGI-30,HSPC143,MGC61450,NPD015
  • Gene Description:
  • DPH5 homolog (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a component of the diphthamide synthesis pathway. Diphthamide is a post-translationally modified histidine residue found only on translation elongation factor 2. It is conserved from archaebacteria to humans, and is targeted by diphtheria toxin and Pseudomonas exotoxin A to halt cellular protein synthesis. The yeast and Chinese hamster homologs of this protein catalyze the trimethylation of the histidine residue on elongation factor 2, resulting in a diphthine moiety that is subsequently amidated to yield diphthamide. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000012522,OTTHUMP00000012523,OTTHUMP00000012524,diphthamide biosynthesis methyltransferase,diphthine synthase,protein x 0011
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