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Last updated: 2016/10/23
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NAGPA polyclonal antibody (A01)

  • Catalog # : H00051172-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant NAGPA.
  • Immunogen:
  • NAGPA (NP_057340, 309 a.a. ~ 408 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00051172-A01
    Western Blot detection against Immunogen (37.11 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Western Blot (Recombinant protein)
  • Gene Information
  • Gene Name:
  • Gene Alias:
  • Gene Description:
  • N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
  • Gene Summary:
  • Hydrolases are transported to lysosomes after binding to mannose 6-phosphate receptors in the trans-Golgi network. This gene encodes the enzyme that catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal hydrolases. Commonly known as 'uncovering enzyme' or UCE, this enzyme removes N-acetyl-D-glucosamine (GlcNAc) residues from GlcNAc-alpha-P-mannose moieties and thereby produces the recognition marker. This reaction most likely occurs in the trans-Golgi network. This enzyme functions as a homotetramer of two disulfide-linked homodimers. In addition to having an N-terminal signal peptide, the protein's C-terminus contains multiple signals for trafficking it between lysosomes, the plasma membrane, and trans-Golgi network. [provided by RefSeq
  • Other Designations:
  • alpha-N-acetylglucosaminyl phosphodiesterase,lysosomal alpha-N-acetylglucosaminidase,mannose 6-phosphate-uncovering enzyme,phosphodiester alpha-GlcNAcase
  • Gene Pathway
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