RDH8 MaxPab mouse polyclonal antibody (B01P)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of RDH8 expression in transfected 293T cell line (H00050700-T01) by RDH8 MaxPab polyclonal antibody.
Lane 1: RDH8 transfected lysate(34.21 KDa).
Lane 2: Non-transfected lysate.
-
Specification
Product Description
Mouse polyclonal antibody raised against a full-length human RDH8 protein.
Immunogen
RDH8 (AAI46480.1, 1 a.a. ~ 311 a.a) full-length human protein.
Sequence
MAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCSDESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQAIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRTTHRLLFRCPRLLNLGLQCLSCGCLPTRVRPR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (82); Rat (83)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Transfected lysate)
Western Blot analysis of RDH8 expression in transfected 293T cell line (H00050700-T01) by RDH8 MaxPab polyclonal antibody.
Lane 1: RDH8 transfected lysate(34.21 KDa).
Lane 2: Non-transfected lysate.
-
Gene Info — RDH8
Entrez GeneID
50700GeneBank Accession#
BC146479Protein Accession#
AAI46480.1Gene Name
RDH8
Gene Alias
PRRDH, SDR28C2
Gene Description
retinol dehydrogenase 8 (all-trans)
Omim ID
608575Gene Ontology
HyperlinkGene Summary
All-trans-retinol dehydrogenase (RDH8) is a visual cycle enzyme that reduces all-trans-retinal to all-trans-retinol in the presence of NADPH (Rattner et al., 2000 [PubMed 10753906]). It is a member of the short chain dehydrogenase/reductase family and is located in the outer segments of photoreceptors; hence it is also known as photoreceptor retinol dehydrogenase. It is important in the visual cycle by beginning the rhodopsin regeneration pathway by reducing all-trans-retinal, the product of bleached and hydrolysed rhodopsin (Rando, 2001 [PubMed 11710234]). This is a rate-limiting step in the visual cycle (Saari et al., 1998 [PubMed 9667000]).[supplied by OMIM
Other Designations
photoreceptor outer segment all-trans retinol dehydrogenase|short chain dehydrogenase/reductase family 28C, member 2
-
Pathway
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com