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DUOX2 rabbit monoclonal antibody

  • Catalog # : H00050506-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human DUOX2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human DUOX2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human DUOX2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • GeneBank Accession#:
  • DUOX2
  • Gene Name:
  • DUOX2
  • Gene Alias:
  • LNOX2,NOXEF2,P138-TOX,THOX2
  • Gene Description:
  • dual oxidase 2
  • Gene Summary:
  • The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes this encoded protein and DUOX1. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. [provided by RefSeq
  • Other Designations:
  • NADH/NADPH thyroid oxidase p138-tox,NADPH oxidase/peroxidase DUOX2,NADPH thyroid oxidase 2,OTTHUMP00000162044,dual oxidase-like domains 2,flavoprotein NADPH oxidase,nicotinamide adenine dinucleotide phosphate oxidase
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