Immunoprecipitation of RAD54B transfected lysate using anti-RAD54B MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with RAD54B MaxPab mouse polyclonal antibody (B01) (H00025788-B01).
The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq
Fibrinogen silencer-binding protein,RAD54 homolog B,RAD54, S. cerevisiae, homolog of, B,fibrinogen silencer binding protein