CDC42EP4 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human CDC42EP4 peptide using ARM Technology.
Immunogen
A synthetic peptide of human CDC42EP4 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human CDC42EP4 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — CDC42EP4
Entrez GeneID
23580GeneBank Accession#
CDC42EP4Gene Name
CDC42EP4
Gene Alias
BORG4, CEP4, KAIA1777, MGC17125, MGC3740
Gene Description
CDC42 effector protein (Rho GTPase binding) 4
Omim ID
605468Gene Ontology
HyperlinkGene Summary
The product of this gene is a member of the CDC42-binding protein family. Members of this family interact with Rho family GTPases and regulate the organization of the actin cytoskeleton. This protein has been shown to bind both CDC42 and TC10 GTPases in a GTP-dependent manner. When overexpressed in fibroblasts, this protein was able to induce pseudopodia formation, which suggested a role in inducing actin filament assembly and cell shape control. [provided by RefSeq
Other Designations
Cdc42 effector protein 4|binder of Rho GTPases 4
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Interactome
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