POFUT1 monoclonal antibody (M01), clone 3H1
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant POFUT1.
Immunogen
POFUT1 (NP_758436, 85 a.a. ~ 194 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VSYQKYFKLEPLQAYHRVISLEDFMEKLAPTHWPPEKRVAYCFEVAAQRSPDKKTCPMKEGNPFGPFWDQFHVSFNKSELFTGISFSASYREQWSQRRENHSCVTLLFPR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (89)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged POFUT1 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — POFUT1
Entrez GeneID
23509GeneBank Accession#
NM_172236Protein Accession#
NP_758436Gene Name
POFUT1
Gene Alias
FUT12, KIAA0180, MGC2482, O-FUT, O-Fuc-T, O-FucT-1
Gene Description
protein O-fucosyltransferase 1
Omim ID
607491Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
GDP-fucose protein O-fucosyltransferase 1|OTTHUMP00000030583|OTTHUMP00000030584|o-fucosyltransferase protein
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Interactomes
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Diseases
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