NCOA6 monoclonal antibody (M01), clone 2D7
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant NCOA6.
Immunogen
NCOA6 (NP_054790, 1954 a.a. ~ 2063 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
VGSHPELLPSIAPSQNLVSKETSTTALQASVARPELEVNAAIVSGQSSEPKEIVEKSKIPGRRNSRTEEPTVASESVENGHRKRSSRPASASSSTKDITSAVQSKRRKSK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (86)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
NCOA6 monoclonal antibody (M01), clone 2D7 Western Blot analysis of NCOA6 expression in Hela S3 NE ( Cat # L013V3 ).Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to NCOA6 on HeLa cell. [antibody concentration 10 ug/ml] -
Gene Info — NCOA6
Entrez GeneID
23054GeneBank Accession#
NM_014071Protein Accession#
NP_054790Gene Name
NCOA6
Gene Alias
AIB3, ANTP, ASC2, HOX1.1, HOXA7, KIAA0181, NRC, PRIP, RAP250, TRBP
Gene Description
nuclear receptor coactivator 6
Omim ID
605299Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. The encoded protein may also act as a general coactivator since it has been shown to interact with some basal transcription factors, histone acetyltransferases, and methyltransferases. [provided by RefSeq
Other Designations
OTTHUMP00000030705|activating signal cointegrator-2|amplified in breast cancer-3 protein|nuclear receptor coactivator RAP250|peroxisome proliferator-activated receptor interacting protein|thyroid hormone receptor binding protein
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Interactome
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Disease
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