NCOA6 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western Blot analysis of HEL cell lysate with NCOA6 polyclonal antibody (Cat # PAB30685).
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with NCOA6 polyclonal antibody (Cat # PAB30685) shows nuclear positivity in cells of tubules and glomeruli.
Immunofluorescence
Immunofluorescent staining of U-251 MG with NCOA6 polyclonal antibody (Cat # PAB30685) (Green) shows positivity in vesicles and nucleus but excluded from the nucleoli.
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Specification
Product Description
Rabbit polyclonal antibody raised against partial recombinant human NCOA6.
Immunogen
Recombinant protein corresponding to human NCOA6.
Sequence
NQNVQHAGGQGAGPPQNQMQVSHGPPNMMQPSLMGIHGNMNNQQAGTSGVPQVNLSNMQGQPQQGPPSQLMGMHQQIVPSQGQMVQQQGTLNPQNPMILSRAQLMPQGQMMVNPPSQNLGPSPQRMTPPKQ
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Antigen affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1-4 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-1:200)
Western Blot (1:100-1:250)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (40% glycerol, 0.02% sodium azide).
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western Blot analysis of HEL cell lysate with NCOA6 polyclonal antibody (Cat # PAB30685).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human kidney with NCOA6 polyclonal antibody (Cat # PAB30685) shows nuclear positivity in cells of tubules and glomeruli.Immunofluorescence
Immunofluorescent staining of U-251 MG with NCOA6 polyclonal antibody (Cat # PAB30685) (Green) shows positivity in vesicles and nucleus but excluded from the nucleoli. -
Gene Info — NCOA6
Entrez GeneID
23054Protein Accession#
Q14686Gene Name
NCOA6
Gene Alias
AIB3, ANTP, ASC2, HOX1.1, HOXA7, KIAA0181, NRC, PRIP, RAP250, TRBP
Gene Description
nuclear receptor coactivator 6
Omim ID
605299Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. The encoded protein may also act as a general coactivator since it has been shown to interact with some basal transcription factors, histone acetyltransferases, and methyltransferases. [provided by RefSeq
Other Designations
OTTHUMP00000030705|activating signal cointegrator-2|amplified in breast cancer-3 protein|nuclear receptor coactivator RAP250|peroxisome proliferator-activated receptor interacting protein|thyroid hormone receptor binding protein
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Interactome
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Disease
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