TMED10 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TMED10 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MSGLSGPPARRGPFPLALLLLFLLGPRLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — TMED10
Entrez GeneID
10972GeneBank Accession#
BC001496Protein Accession#
no protein_accGene Name
TMED10
Gene Alias
P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I
Gene Description
transmembrane emp24-like trafficking protein 10 (yeast)
Omim ID
605406Gene Ontology
HyperlinkGene Summary
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq
Other Designations
21 kDa transmembrane trafficking protein|transmembrane emp24 domain-containing protein 10
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Interactome
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Disease
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