TMED10 purified MaxPab mouse polyclonal antibody (B01P)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human TMED10 protein.
Immunogen
TMED10 (ADZ15823.1, 1 a.a. ~ 219 a.a) full-length human protein.
Sequence
MSGLSGPPARRGPFPLALLLLFLLGPRLVLAISFHLPINSRKCLREEIHKDLLVTGAYEISDQSGGAGGLRSHLKITDSAGHILYSKEDATKGKFAFTTEDYDMFEVCFESKGTGRIPDQLVILDMKHGVEAKNYEEIAKVEKLKPLEVELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNTRVLYFSIFSMFCLIGLATWQVFYLRRFFKAKKLIE
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (93)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
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Gene Info — TMED10
Entrez GeneID
10972GeneBank Accession#
JF432606.1Protein Accession#
ADZ15823.1Gene Name
TMED10
Gene Alias
P24(DELTA), S31I125, S31III125, TMP21, Tmp-21-I
Gene Description
transmembrane emp24-like trafficking protein 10 (yeast)
Omim ID
605406Gene Ontology
HyperlinkGene Summary
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq
Other Designations
21 kDa transmembrane trafficking protein|transmembrane emp24 domain-containing protein 10
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