YAF2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human YAF2 full-length ORF ( NP_005739.2, 1 a.a. - 180 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MGDKKSPTRPKRQPKPSSDEGYWDCSVCTFRNSAEAFKCMMCDVRKGTSTRKPRPVSQLVAQQVTQQFVPPTQSKKEKKDKVEKEKSEKETTSKKNSHKKTRPRLKNVDRSSAQHLEVTVGDLTVIITDFKEKTKSPPASSAASADQHSQSGSSSDNTERGMSRSSSPRGEASSLNGESH
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
46.3
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — YAF2
Entrez GeneID
10138GeneBank Accession#
NM_005748.3Protein Accession#
NP_005739.2Gene Name
YAF2
Gene Alias
MGC41856
Gene Description
YY1 associated factor 2
Omim ID
607534Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene interacts with YY1, a zinc finger protein involved in negative regulation of muscle-restricted genes. This gene product itself contains a single N-terminal C2-X10-C2 zinc finger, and in contrast to YY1, is up-regulated during myogenic differentiation. It also facilitates proteolytic cleavage of YY1 by the calcium- activated protease, m-calpain, suggesting a mechanism by which this protein antagonizes the negative effect of YY1. [provided by RefSeq
Other Designations
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Interactome
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Disease
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