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Last updated: 2016/11/27

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PDCD6IP rabbit monoclonal antibody

  • Catalog # : H00010015-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PDCD6IP peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PDCD6IP is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PDCD6IP peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Gene Name:
  • PDCD6IP
  • Gene Alias:
  • AIP1,Alix,DRIP4,HP95,MGC17003
  • Gene Description:
  • programmed cell death 6 interacting protein
  • Gene Summary:
  • This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • ALG-2 interacting protein 1,ALG-2 interacting protein X,apoptosis-linked gene 2-interacting protein X,dopamine receptor interacting protein 4,programmed cell death 6-interacting protein
  • Gene Pathway
  • Related Disease
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