PDCD6IP recombinant monoclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of CHOK1 (A), rat brain (B), Jurkat (C) whole cell lysates with ALIX recombinant monoclonal antibody (Cat # RAB02465).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human PDCD6IP.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against recombinant protein of human ALIX.
Theoretical MW (kDa)
100
Reactivity
Hamster, Human, Rat
Specificity
Recognizes endogenous levels of ALIX protein.
Form
Liquid
Purification
Immunogen affinity chromatography
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50mM Tris-Glycine, pH 7.4 (0.15M NaCl, 50% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at 4°C short term.
Aliquot and store at -20°C long term.
Avoid freeze-thaw cycles.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of CHOK1 (A), rat brain (B), Jurkat (C) whole cell lysates with ALIX recombinant monoclonal antibody (Cat # RAB02465). -
Gene Info — PDCD6IP
Entrez GeneID
10015Protein Accession#
Q8WUM4Gene Name
PDCD6IP
Gene Alias
AIP1, Alix, DRIP4, HP95, MGC17003
Gene Description
programmed cell death 6 interacting protein
Omim ID
608074Gene Ontology
HyperlinkGene Summary
This gene encodes a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
ALG-2 interacting protein 1|ALG-2 interacting protein X|apoptosis-linked gene 2-interacting protein X|dopamine receptor interacting protein 4|programmed cell death 6-interacting protein
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Interactome
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Pathway
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Disease
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