HEPH monoclonal antibody (M01), clone 2D3
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant HEPH.
Immunogen
HEPH (NP_620074, 315 a.a. ~ 424 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
TRGHHTDVANIFPATFVTAEMVPWEPGTWLISCQVNSHFRDGMQALYKVKSCSMAPPVDLLTGKVRQYFIEAHEIQWDYGPMGHDGSTGKNLREPGSISDKFFQKSSSRI
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (83); Rat (80)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HEPH is approximately 0.3ng/ml as a capture antibody.ELISA
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Gene Info — HEPH
Entrez GeneID
9843GeneBank Accession#
NM_138737Protein Accession#
NP_620074Gene Name
HEPH
Gene Alias
CPL, KIAA0698
Gene Description
hephaestin
Omim ID
300167Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is similar to an iron transport protein found in mouse. The mouse protein is similar to ceruloplasmin, a serum multi-copper ferroxidase, and is thought to be a membrane-bound protein responsible for transport of dietary iron from epithelial cells of the intestinal lumen into the circulatory system. In mouse, defects in this gene can lead to severe microcytic anemia. Three transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000023443|OTTHUMP00000023444|OTTHUMP00000023445
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Interactome
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Disease
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