PLEKHM1 monoclonal antibody (M01), clone 1C9
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant PLEKHM1.
Immunogen
PLEKHM1 (AAH64361, 957 a.a. ~ 1056 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PHRFSVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHHDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (93); Rat (93)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PLEKHM1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — PLEKHM1
Entrez GeneID
9842GeneBank Accession#
BC064361Protein Accession#
AAH64361Gene Name
PLEKHM1
Gene Alias
AP162, B2, KIAA0356, OPTB6
Gene Description
pleckstrin homology domain containing, family M (with RUN domain) member 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is essential for bone resorption, and may play a critical role in vesicular transport in the osteoclast. Mutations in this gene are associated with autosomal recessive osteopetrosis type 6 (OPTB6). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq
Other Designations
adapter protein 162
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