KLK4 monoclonal antibody (M09), clone 2A4
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KLK4.
Immunogen
KLK4 (NP_004908.2, 159 a.a. ~ 254 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQDQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQAS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (70)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.3 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KLK4 expression in transfected 293T cell line by KLK4 monoclonal antibody (M09), clone 2A4.
Lane 1: KLK4 transfected lysate (Predicted MW: 27 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KLK4 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — KLK4
Entrez GeneID
9622GeneBank Accession#
NM_004917Protein Accession#
NP_004908.2Gene Name
KLK4
Gene Alias
ARM1, EMSP, EMSP1, KLK-L1, MGC116827, MGC116828, PROSTASE, PRSS17, PSTS
Gene Description
kallikrein-related peptidase 4
Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. In some tissues its expression is hormonally regulated. The expression pattern of a similar mouse protein in murine developing teeth supports a role for the protein in the degradation of enamel proteins. Alternate splice variants for this gene have been described, but their biological validity has not been determined. [provided by RefSeq
Other Designations
androgen-regulated message 1|enamel matrix serine protease 1|kallikrein 4 (prostase, enamel matrix, prostate)|kallikrein-like protein 1|protease, serine, 17
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Interactome
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Disease
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